Jeanie begins to realize the burden of living an HIV-positive life when bills start mounting up and Benton throws her out of a trauma. The staff nervously awaits news on the hospital's future when it's rumored to be closing. As it turns out, Southside is closed instead, and County takes on a new chief of staff, Dr. Anspaugh. Mark and Susan endure disastrous blind dates. Benton sends Carter to the ER for the day after he arrives late. Carter then talks a patient into a local anesthetic and encourages him to ask Benton questions during the operation.

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